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首页-小分子抑制剂&激动剂-Others-Amyloids-SO286
SO286

Chemical Structure : SO286

CAS No.: 70878-37-4

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SO286 (SO-286)

货号: PC-27705Not For Human Use, Lab Use Only.

SO286 is a small molecule ubiquilin-2 (UBQLN2) inhibitor with SPR KD of 0.351 uM, binds to the STI1 region of UBQLN2, blocking its liquid-gel/solid transition and interaction with α-synuclein (α-syn), thereby suppressing α-syn aggregation, shows neuroprotective activity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

SO286 is a small molecule ubiquilin-2 (UBQLN2) inhibitor with SPR KD of 0.351 uM, binds to the STI1 region of UBQLN2, blocking its liquid-gel/solid transition and interaction with α-synuclein (α-syn), thereby suppressing α-syn aggregation, shows neuroprotective activity.

物理化学性质&存储条件

分子量 596.59
分子式 C34H28O10
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1,2,3,6-tetra-O-benzoyl-muco-inositol

参考文献

1. Takei T, et al. EMBO J. 2025 Nov;44(22):6527-6555.

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