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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Cyclin-dependent Kinase (CDK)-SNX9-1
SNX9-1

Chemical Structure : SNX9-1

CAS No.: 2447-23-6

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SNX9-1

货号: PC-25576Not For Human Use, Lab Use Only.

SNX9-1 is a potent, specific cyclin-dependent kinase 3 (CDK3) inhibitor with IC50 of 1.58 uM, is potent in preventing the induction of transcription by p21 (IC50=15.9 uM) and growth inhibition of the HT1080-based reporter cell line (IC50=9.3 uM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

SNX9-1 is a potent, specific cyclin-dependent kinase 3 (CDK3) inhibitor with IC50 of 1.58 uM, is potent in preventing the induction of transcription by p21 (IC50=15.9 uM) and growth inhibition of the HT1080-based reporter cell line (IC50=9.3 uM).

物理化学性质&存储条件

分子量 229.10
分子式 C10H10Cl2N2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2- (5,7-dichloro-1H-indol-3-yl)ethan-1-amine

参考文献

1. Patent WO2014089450 A1.

2. Theodosia Teo, et al. Pharmacol Res. 2022 Jun:180:106249.

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