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首页-小分子抑制剂&激动剂-GPCR-Melanocortin Receptor-SNT-207707
SNT-207707

Chemical Structure : SNT-207707

CAS No.: 1064662-40-3

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SNT-207707 (SNT207707)

货号: PC-49762Not For Human Use, Lab Use Only.

SNT-207707 (SNT207707) is a potent, selective, BBB-penetrating, and orally active melanocortin-4 (MC-4) receptor antagonist with binding/fuaction IC50 of 8/5 nM, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    SNT-207707 (SNT207707) is a potent, selective, BBB-penetrating, and orally active melanocortin-4 (MC-4) receptor antagonist with binding/fuaction IC50 of 8/5 nM, respectively.
    SNT-207707 treatment increase food intake in healthy mice.
    SNT-207707 prevented tumor induced weight loss, and diminished loss of lean body mass and fat mass.

    物理化学性质&存储条件

    分子量 550.19
    分子式 C32H44ClN5O
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-(4-cyanophenyl)-N,N-diisopentyl-3-(3-(pyrrolidin-1-yl)propyl)imidazo[1,2-a]pyridine-6-carboxamide hydrochloride

    参考文献

    1. Weyermann P, et al. PLoS One. 2009;4(3):e4774.

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