SNAP-94847 hydrochloride | MCHR1 inhibitor | Probechem Biochemicals

Chemical Structure : SNAP-94847 hydrochloride

CAS No.: 1781934-47-1

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SNAP-94847 hydrochloride (SNAP94847 hydrochloride)

货号: PC-61526Not For Human Use, Lab Use Only.

SNAP-94847 hydrochloride is a selective, high-affinity, and competitive MCH1 receptor (MCHR1) antagonist with Ki of 1.69 nM.

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5 mg	￥2280	In stock
10 mg	￥3580	In stock
25 mg	￥4980	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

SNAP-94847 hydrochloride is a selective, high-affinity, and competitive MCH1 receptor (MCHR1) antagonist with Ki of 1.69 nM.
SNAP-94847 displays an anxiolytic/antidepressant-like effect in mouse models, stimulates the proliferation of progenitors in the dentate gyrus.
SNAP-94847 has a unique anxiolytic-like profile that is distinct from selective serotonin reuptake inhibitors and tricyclic antidepressants.

物理化学性质&存储条件

分子量	515.042
分子式	C29H32F2N2O2.HCl
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-{1-[4-(3,4-Difluorophenoxy)benzyl]-4-piperidinyl}-4-methylphenyl)-2-methylpropanamide hydrochloride

参考文献

1. David DJ, et al. J Pharmacol Exp Ther. 2007 Apr;321(1):237-48.

2. Chen CA, et al. J Med Chem. 2007 Aug 9;50(16):3883-90.

3. Nair SG, et al. Psychopharmacology (Berl). 2009 Jul;205(1):129-40.

SNAP-94847 hydrochloride (SNAP94847 hydrochloride)

生物&药学活性

物理化学性质&存储条件

参考文献

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SNAP-94847 hydrochloride (SNAP94847 hydrochloride)

生物&药学活性

物理化学性质&存储条件

参考文献

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