SN38023 | DNA-PK inhibitor | Probechem Biochemicals

Chemical Structure : SN38023

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SN38023 (SN 38023)

货号: PC-20221Not For Human Use, Lab Use Only.

SN38023 is a bioreductive prodrug of DNA-dependent protein kinase inhibitor IC87361 (Cat# PC-62995), SN38023 is metabolised to a potent DNA-PKi (IC87361) selectively in radioresistant hypoxic cells.

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25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

SN38023 is a bioreductive prodrug of DNA-dependent protein kinase inhibitor IC87361 (Cat# PC-62995), SN38023 is metabolised to a potent DNA-PKi (IC87361) selectively in radioresistant hypoxic cells.

物理化学性质&存储条件

分子量	462.46
分子式	C24H22N4O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-[(1-Methyl-2-nitro-1H-imidazol-5-yl)methoxy]-7-(4-morpholinyl)-2-phenyl-4H-1-benzopyran-4-one

参考文献

1. Way Wua Wong, et al. Biochem Pharmacol. 2019 Nov;169:113641.

SN38023 (SN 38023)

生物&药学活性

物理化学性质&存储条件

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SN38023 (SN 38023)

生物&药学活性

物理化学性质&存储条件

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