SN34960 | Perforin inhibitor | Probechem Biochemicals

Chemical Structure : SN34960

CAS No.: 1567836-70-7

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SN34960 (SN 34960)

货号: PC-20609Not For Human Use, Lab Use Only.

SN34960 is a small molecule Perforin inhibitor, inhibits perforin-induced lysis of Jurkat T-lymphoma cells with IC50 of 6.65 uM, shows suboptimal physicochemical properties and toxicity toward the natural killer (NK) cells that secrete perforin in vivo.

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5 mg	￥2480	In stock
10 mg	￥3880	In stock
25 mg	￥5980	In stock
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100 mg		Get quote

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SN34960 is a small molecule Perforin inhibitor, inhibits perforin-induced lysis of Jurkat T-lymphoma cells with IC50 of 6.65 uM, shows suboptimal physicochemical properties and toxicity toward the natural killer (NK) cells that secrete perforin in vivo.

物理化学性质&存储条件

分子量	506.55
分子式	C24H18N4O5S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)-2-nitrobenzenesulfonamide

参考文献

1. Julie A. Spicer, et al. J. Med. Chem. 2022, 65, 21, 14305–14325

2. M Welz, et al. Nat Commun. 2018 Nov 15;9(1):4805.

SN34960 (SN 34960)

生物&药学活性

物理化学性质&存储条件

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SN34960 (SN 34960)

生物&药学活性

物理化学性质&存储条件

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