SMN-C3 | SMN2 splicing modulator | Probechem Biochemicals

Chemical Structure : SMN-C3

CAS No.: 1449597-34-5

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SMN-C3 (SMN2 splicing modulator)

货号: PC-62675Not For Human Use, Lab Use Only.

SMN-C3 is a selective, orally available small molecule SMN2 splicing modifier toward the production of full-length SMN2 messenger RNA with high selectivity.

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10 mg	￥5980	In stock
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生物&药学活性

SMN-C3 is a selective, orally available small molecule SMN2 splicing modifier toward the production of full-length SMN2 messenger RNA with high selectivity.
SMN-C3 increases SMN protein levels, improves motor function, and protects of the neuromuscular circuit in Δ7 mice.
SMN-C3 also extends the life span of the mice.

物理化学性质&存储条件

分子量	416.529
分子式	C24H28N6O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4H-Pyrido[1,2-a]pyrimidin-4-one, 2-(4,6-dimethylpyrazolo[1,5-a]pyrazin-2-yl)-7-(1-ethyl-4-piperidinyl)-9-methyl-

参考文献

1. Naryshkin NA, et al. Science. 2014 Aug 8;345(6197):688-93.

SMN-C3 (SMN2 splicing modulator)

生物&药学活性

物理化学性质&存储条件

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SMN-C3 (SMN2 splicing modulator)

生物&药学活性

物理化学性质&存储条件

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