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首页-小分子抑制剂&激动剂-NF-κB Pathway-NF-κB-SMEPPI
SMEPPI

Chemical Structure : SMEPPI

CAS No.: 1274881-60-5

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SMEPPI

货号: PC-23849Not For Human Use, Lab Use Only.

SMEPPI is a small molecule inhibitor of expression and activation of NF-κB p65, induces NF-κB p65 proteasomal degradation and has anti-diabetic and anti-inflammatory activities.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

SMEPPI is a small molecule inhibitor of expression and activation of NF-κB p65, induces NF-κB p65 proteasomal degradation and has anti-diabetic and anti-inflammatory activities.

物理化学性质&存储条件

分子量 526.55
分子式 C27H24F2N2O5S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
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Solubility

10 mM in DMSO
Chemical Name/SMILES

6-(2-(1,1-dioxidothiomorpholino) ethoxy)-3-(2,4-difluorophenyl)-2-(6-methoxypyridin-3-yl)-1H-inden-1-one

参考文献

1. Ji Hyun Oh, et al. Biomed Pharmacother. 2025 Jan 14:183:117856.

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