SMEI inhibitor 20e

Chemical Structure : SMEI inhibitor 20e

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货号: PC-26454Not For Human Use, Lab Use Only.

SMEI inhibitor 20e is a small molecule inhibitor targeting SCN1A-associated severe myoclonic epilepsy of infancy (SMEI), shows potent antiseizure efficacy in zebrafish behavioral assays and significantly reduces locomotion-related seizure parameters, elevates 5-HT levels via TPH2 upregulation.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

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生物&药学活性

物理化学性质&存储条件

分子量	373.69
分子式	C15H8ClF4N3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(2-Chloro-4-fluorobenzyl)-5-(2-(trifluoromethyl)pyridin-4-yl)-1,3,4-oxadiazol-2(3H)-one

参考文献

1. Kim DG, et al. J Med Chem. 2026 Feb 12;69(3):3362-3377.