SMARt-420 (BDM 41420) |CAS:1616242-21-7 Probechem Biochemicals

Chemical Structure : SMARt-420

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SMARt-420 (BDM 41420)

货号: PC-62330Not For Human Use, Lab Use Only.

SMARt-420 (BDM 41420) is a small molecule that can fully reverses ethionamide-acquired resistance and clears ethionamide-resistant M. tuberculosis infection in mice, also increases the basal sensitivity of bacteria to ethionamide.

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生物&药学活性

物理化学性质&存储条件

分子量	340.346
分子式	C17H19F3N2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4,4,4-Trifluoro-1-(3-phenyl-1-oxa-2,8-diaza-spiro[4.5]dec-2-en-8-yl)-butan-1-one

参考文献

1. Blondiaux N, et al. Science. 2017 Mar 17;355(6330):1206-1211.

2. Wohlkönig A, et al. Biochem Biophys Res Commun. 2017 May 27;487(2):403-408.