Chemical Structure : SLU-PP-915
CAS No.: 2285432-92-8
货号: PC-20982Not For Human Use, Lab Use Only.
SLU-PP-915 is a potent pan-ERR (Estrogen-related receptor) nuclear receptor agonist with EC50 of 414/435/378 nM for ERRα/ERRβ/ERRγ, respectively.
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SLU-PP-915 is a potent pan-ERR (Estrogen-related receptor) nuclear receptor agonist with EC50 of 414/435/378 nM for ERRα/ERRβ/ERRγ, respectively.
SLU-PP-915 (5 uM) increased levels of gene expression (PGC1α, PDK4 and LDHA) in C2C12 myoblast cells.
SLU-PP-915 (20 mg/kg, i.p) ) induced expression of ERR target genes in muscles.
分子量 | 341.16 | |
分子式 | C17H13BFNO3S | |
外观性状 | Solid | |
储存条件 |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
(3-(5-((2-fluorophenyl)carbamoyl)thiophen-2-yl)phenyl)boronic acid |
1. Hampton CS, et al. Eur J Med Chem. 2023 Jun 25;258:115582.
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