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SLU-1642

Chemical Structure : SLU-1642

CAS No.: 2822535-92-0

SLU-1642 (SLU1642)

货号: PC-28760Not For Human Use, Lab Use Only.

SLU-1642 is a specific small-molecule inhibitor that selectively targets P. aeruginosa MexF and its closest homologs, but not major efflux pumps such as MexB, specifically potentiates the activity of antibiotic substrates of MexF in P. aeruginosa hyperporinated strains overexpressing MexF.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

SLU-1642 is a specific small-molecule inhibitor that selectively targets P. aeruginosa MexF and its closest homologs, but not major efflux pumps such as MexB, specifically potentiates the activity of antibiotic substrates of MexF in P. aeruginosa hyperporinated strains overexpressing MexF.

物理化学性质&存储条件

分子量 360.90
分子式 C18H21ClN4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(3-(1H-imidazol-1-yl)propyl)-6-chloro-N-(cyclopropylmethyl)-4-methylbenzo[d]thiazol-2-amine

参考文献

1. Uddin MR, et al. Antimicrob Agents Chemother. 2026 Nov 2:e0070626.

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