SLMP53-1 |CAS:1643469-17-3 Probechem Biochemicals

Chemical Structure : SLMP53-1

CAS No.: 1643469-17-3

加入收藏

SLMP53-1 (p53 reactivator SLMP53-1)

货号: PC-61497Not For Human Use, Lab Use Only.

SLMP53-1 is a small molecule reactivator of wild-type and mutant p53, shows a p53-dependent anti-proliferative activity in human wt and mut p53R280K-expressing tumor cells.

规格	价格	库存
5 mg	￥2880	In stock
10 mg	￥4780	In stock
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

SLMP53-1 is a small molecule reactivator of wild-type and mutant p53, shows a p53-dependent anti-proliferative activity in human wt and mut p53R280K-expressing tumor cells.
SLMP53-1 enhances p53 transcriptional activity and restores wt-like DNA binding ability to mut p53R280K.
SLMP53-1 inhibits the growth of wt/mut p53-expressing tumors in xenograft mice models, without apparent toxicity.

物理化学性质&存储条件

分子量	318.376
分子式	C20H18N2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(3S,9bR)-3-((1H-indol-3-yl)methyl)-9b-methyl-2,3-dihydrooxazolo[2,3-a]isoindol-5(9bH)-one

参考文献

1. Soares J, et al. Oncotarget. 2016 Jan 26;7(4):4326-43.

SLMP53-1 (p53 reactivator SLMP53-1)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

SLMP53-1 (p53 reactivator SLMP53-1)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.