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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Sphingosine kinase (SphK)-SLL3071511
SLL3071511

Chemical Structure : SLL3071511

CAS No.: 2768854-76-6

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SLL3071511 (SLL 3071511)

货号: PC-47034Not For Human Use, Lab Use Only.

SLL3071511 is a novel potent inhibitor of Chikungunya virus (CHIKV) infection with EC50 of 2.91 uM, inhibits sphingosine kinase SK1 and SK2 with Ki values of 0.27 and 0.66 uM, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    SLL3071511 is a novel potent inhibitor of Chikungunya virus (CHIKV) infection with EC50 of 2.91 uM, inhibits sphingosine kinase SK1 and SK2 with Ki values of 0.27 and 0.66 uM, respectively.
    SLL3071511 is potent against CHIKV infection during early infection, decreasing the infectious virus production, and significantly decreasing the viral RNA expression.

    物理化学性质&存储条件

    分子量 345.571
    分子式 C23H39NO
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (R)-(1-(4-undecylbenzyl)pyrrolidin-2-yl)methanol

    参考文献

    1. Oyewole OO, et al. Viruses. 2022 May 24;14(6):1123.

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