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首页-小分子抑制剂&激动剂-Others-Other Targets-SLC6A19 inhibitor 39
SLC6A19 inhibitor 39

Chemical Structure : SLC6A19 inhibitor 39

CAS No.: 2755929-52-1

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SLC6A19 inhibitor 39

货号: PC-38115Not For Human Use, Lab Use Only.

SLC6A19 inhibitor 39 is a potent, selective and orally efficacious inhibitor of neutral amino acid transporter B0AT1 (SLC6A19) with IC50 of 35 nM.

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2 mg ￥2780 In stock
5 mg ￥4580 In stock
10 mg ￥7280 In stock
50 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SLC6A19 inhibitor 39 is a potent, selective and orally efficacious inhibitor of neutral amino acid transporter B0AT1 (SLC6A19) with IC50 of 35 nM.
SLC6A19 inhibitor 39 exhibits excellent pharmacokinetic profile (%F: 66) in mice and efficacious in vivo in diet induced obese (DIO) mice model.

物理化学性质&存储条件

分子量 493.419
分子式 C19H12F5NO5S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-[2-(3,5-Difluorophenoxy)-4-[(trifluoromethyl)sulfonyl]phenyl]benzenesulfonamide

参考文献

1. Jigar Desai, et al. Bioorg Med Chem Lett. 2021 Dec 1;53:128421.

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