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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Glutamate Transporter-SLC1A1-IN-1
SLC1A1-IN-1

Chemical Structure : SLC1A1-IN-1

CAS No.: 2387446-20-8

SLC1A1-IN-1 (EAAT3-IN-1)

货号: PC-26610Not For Human Use, Lab Use Only.

SLC1A1/EAAT3-IN-1 is a selective SLC1A1(excitatory amino acid transporter subtype 3, EAAT3) inhibitor with IC50 of 7.2 uM, ∼35-fold selectivity for EAAT3 over EAAT1,2,4.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SLC1A1/EAAT3-IN-1 is a selective SLC1A1(excitatory amino acid transporter subtype 3, EAAT3) inhibitor with IC50 of 7.2 uM, ∼35-fold selectivity for EAAT3 over EAAT1,2,4.

物理化学性质&存储条件

分子量 368.23
分子式 C18H14BrN3O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

8-Bromo-2-(furan-2-yl)-N-(o-tolyl)imidazo[1,2-a]pyridin-3-amine

参考文献

1. Peng Wu, et al. ACS Chem Neurosci. 2019 Oct 16;10(10):4414-4429.

2. Koochaki P, et al. EMBO J. 2026 Apr 22. doi: 10.1038/s44318-026-00776-2.

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