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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Pregnane X Receptor (PXR)-SJPYT-328
SJPYT-328

Chemical Structure : SJPYT-328

CAS No.: 2998548-72-2

SJPYT-328 (SJPYT328)

货号: PC-22402Not For Human Use, Lab Use Only.

SJPYT-328 is a potent, selective pregnane X receptor (PXR) agonist with binding IC50 of 48 nM, agonism IC50 of 7.1 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

SJPYT-328 is a potent, selective pregnane X receptor (PXR) agonist with binding IC50 of 48 nM, agonism IC50 of 7.1 nM.

物理化学性质&存储条件

分子量 508.66
分子式 C29H40N4O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-N-(5-(tert-butyl)-2-(hexan-3-yloxy)phenyl)-1-(2,4-dimethoxy-5-methylphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxamide

参考文献

1. Garcia-Maldonado E, et al. Nat Commun. 2024 May 14;15(1):4054.

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