SIRT5 inhibitor 49 | SIRT5 inhibitor | Probechem Biochemicals

Chemical Structure : SIRT5 inhibitor 49

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SIRT5 inhibitor 49 (Sirt5-i)

货号: PC-72767Not For Human Use, Lab Use Only.

SIRT5 inhibitor 49 (Sirt5-i) is a potent and specific SIRT5 inhibitor with IC50 of 0.11 uM.

规格	价格	库存	数量
25 mg		Get quote
100 mg		Get quote
250 mg		Get quote
1 g		Get quote

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生物&药学活性

SIRT5 inhibitor 49 (Sirt5-i) is a potent and specific SIRT5 inhibitor with IC50 of 0.11 uM.
SIRT5 inhibitor 49 also reduced SARS-CoV-2 viral levels in cell-culture experiments.
SIRT5 catalytic domain is necessary for the interaction with Nsp14, but that Nsp14 does not appear to be directly deacylated by SIRT5.

物理化学性质&存储条件

分子量	674.807
分子式	C31H39FN6O6S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 Month
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Solubility
Chemical Name/SMILES

参考文献

1. Nima Rajabi, et al. Angew Chem Int Ed Engl. 2017 Nov 20;56(47):14836-14841.

2. Nima Rajabi, et al. Angew Chem Int Ed Engl. 2022 Mar 17.

3. Walter M, et al. bioRxiv. 2022 Jan 5:2022.01.04.474979.