SIRT5 inhibitor 32

Chemical Structure : SIRT5 inhibitor 32

加入收藏

货号: PC-72766Not For Human Use, Lab Use Only.

SIRT5 inhibitor 32 is an efficient, cellularly active small molecule that targets SIRT5.

规格	价格	库存	数量
25 mg		Get quote
100 mg		Get quote
250 mg		Get quote
1 g		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

SIRT5 inhibitor 32 is an efficient, cellularly active small molecule that targets SIRT5.
SIRT5 inhibitor 32 inhibits cell growth of SIRT5-dependent AML cell lines SKM-1, OCIAML2 and MOLM-13 with IC50 of 9, 20, and 24 uM, respectively.
SIRT5 inhibitor 32 is also shown to inhibit SIRT5 in HeLa cells by using an assay that produce in-cell fluoresence in response to SIRT5 activity in the mitochondria.
SIRT5 inhibitor 32 displays cytoselective toxicity towards SIRT5-dependent AML cells (SKM-1) over HEK293T cells in culture.

物理化学性质&存储条件

分子量	855.062
分子式	C40H55FN10O6S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 Month
Shipping
Solubility
Chemical Name/SMILES

参考文献

1. Nima Rajabi, et al. Angew Chem Int Ed Engl. 2022 Mar 17.