SIRT3 inhibitor 8

Chemical Structure : SIRT3 inhibitor 8

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货号: PC-72772Not For Human Use, Lab Use Only.

SIRT3 inhibitor 8 is a SIRT3 selective inhibitor with IC50 of 6 uM, 6.8- and 5.3-fold selectivity for SIRT3 versus SIRT1 and SIRT2.

规格	价格	库存	数量
25 mg		Get quote
100 mg		Get quote
250 mg		Get quote
1 g		Get quote

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生物&药学活性

SIRT3 inhibitor 8 is a SIRT3 selective inhibitor with IC50 of 6 uM, 6.8- and 5.3-fold selectivity for SIRT3 versus SIRT1 and SIRT2.
SIRT3 inhibitor 8 reduced DLBCL cell viability and triggered activation of autophagy.

物理化学性质&存储条件

分子量	436.511
分子式	C28H24N2O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 Month
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Solubility
Chemical Name/SMILES

参考文献

1. Sumit S Mahajan, et al. J Med Chem. 2014 Apr 24;57(8):3283-94.

2. Meng Li, et al. Cancer Cell. 2019 Jun 10;35(6):916-931.e9.