SIRT2 inhibitor 55

Chemical Structure : SIRT2 inhibitor 55

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货号: PC-72773Not For Human Use, Lab Use Only.

SIRT2 inhibitor 55 is a potent and selective SIRT2 inhibitor with IC50 of 250 nM.

规格	价格	库存	数量
25 mg		Get quote
100 mg		Get quote
250 mg		Get quote
1 g		Get quote

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生物&药学活性

SIRT2 inhibitor 55 is a potent and selective SIRT2 inhibitor with IC50 of 250 nM.
SIRT2 inhibitor 55 displays >300 to >800-fold selectivity over SIRT1 and 3, respectively.
SIRT2 inhibitor 55 dose-dependently increases tubulin acetylation in treated non-small cell lung cancer cell line NCI-H460.
SIRT2 inhibitor 55 shows cytotoxicity in in B-cell lymphoma and other cancer cell lines (Raji cell IC50=11.9 uM).

物理化学性质&存储条件

分子量	551.36
分子式	C25H22BrF3N2O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 Month
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Solubility
Chemical Name/SMILES

参考文献

1. Chowdhury S, et al. Molecules. 2020 Jan 21;25(3):455.