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首页-小分子抑制剂&激动剂-Epigenetics-Sirtuin -SIRT2 inhibitor 33i
SIRT2 inhibitor 33i

Chemical Structure : SIRT2 inhibitor 33i

CAS No.: 1382354-26-8

SIRT2 inhibitor 33i

货号: PC-21145Not For Human Use, Lab Use Only.

SIRT2 inhibitor 33i is a potent, specific Sirtuin 2 (SIRT2) inhibitor with IC50 of 0.57 uM, no activity against SIRT1 and SIRT3 (IC50>100 uM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

SIRT2 inhibitor 33i is a potent, specific Sirtuin 2 (SIRT2) inhibitor with IC50 of 0.57 uM, no activity against SIRT1 and SIRT3 (IC50>100 uM).

物理化学性质&存储条件

分子量 350.39
分子式 C21H19FN2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

O=C(N)C1=CC=CC=C1NC2=CC=CC(OCCC3=CC=CC(F)=C3)=C2

参考文献

1. Takayoshi Suzuki, et al. J Med Chem. 2012 Jun 28;55(12):5760-73.

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