SHP244 |CAS:902891-37-6 Probechem Biochemicals

Chemical Structure : SHP244

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SHP244 (SHP 244, SHP-244)

货号: PC-61822Not For Human Use, Lab Use Only.

SHP244 is a distinct, allosteric site 2 SHP2 inhibitor with IC50 of 60 uM (SHP2 1-525), equipotent on the double mutant (SHP2T253M/Q257L IC50=68 uM), and selective over the phosphatase domain (SHP2 PTP IC50>100 uM)..

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SHP244 is a distinct, allosteric site 2 SHP2 inhibitor with IC50 of 60 uM (SHP2 1-525), equipotent on the double mutant (SHP2T253M/Q257L IC50=68 uM), and selective over the phosphatase domain (SHP2 PTP IC50>100 uM).

物理化学性质&存储条件

分子量	432.864
分子式	C23H17ClN4O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(2-chlorobenzyl)-1-(2-hydroxy-3-methoxyphenyl)-[1,2,4]triazolo[4,3-a]quinazolin-5(4H)-one

参考文献

1. Fodor M, et al. ACS Chem Biol. 2018 Jan 18. doi: 10.1021/acschembio.7b00980.

SHP244 (SHP 244, SHP-244)

生物&药学活性

物理化学性质&存储条件

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SHP244 (SHP 244, SHP-244)

生物&药学活性

物理化学性质&存储条件

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