SGD-1882 |CAS:1222490-34-7 Probechem Biochemicals

Chemical Structure : SGD-1882

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SGD-1882 (PBD dimer;Pyrrolobenzodiazepine dimer)

货号: PC-60141Not For Human Use, Lab Use Only.

PBD dimer;Pyrrolobenzodiazepine dimer novel potent DNA-intercalating payload dimer (PBD dimer) payload for antibody-drug conjugates (ADCs).

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生物&药学活性

SGD-1882 (PBD dimer, Pyrrolobenzodiazepine dimer) is a novel potent DNA-intercalating payload dimer (PBD dimer) payload for antibody-drug conjugates (ADCs).

物理化学性质&存储条件

分子量	725.802
分子式	C42H39N5O7
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-(4-aminophenyl)-7-methoxy-8-(3-(((S)-7-methoxy-2-(4-methoxyphenyl)-5-oxo-5,11a-dihydro-1H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-8-yl)oxy)propoxy)-1,11a-dihydro-5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-5-one

参考文献

1. Sean W. Smith, et al. ACS Med. Chem. Lett. DOI: 10.1021/acsmedchemlett.7b00436

SGD-1882 (PBD dimer;Pyrrolobenzodiazepine dimer)

生物&药学活性

物理化学性质&存储条件

参考文献

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SGD-1882 (PBD dimer;Pyrrolobenzodiazepine dimer)

生物&药学活性

物理化学性质&存储条件

参考文献

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