SGC8158 | PRMT7 inhibitor | Probechem Biochemicals

Chemical Structure : SGC8158

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SGC8158 (SGC-8158, SGC 8158)

货号: PC-72395Not For Human Use, Lab Use Only.

SGC8158 (SGC-8158) is a potent, selective, and SAM-competitive inhibitor of PRMT7 with IC50 of <2.5 nM, the active component of it's cell permeable prodrug SGC3027.

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生物&药学活性

SGC8158 (SGC-8158) is a potent, selective, and SAM-competitive inhibitor of PRMT7 with IC50 of <2.5 nM, the active component of it's cell permeable prodrug SGC3027.

物理化学性质&存储条件

分子量	555.094
分子式	C27H31ClN6O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-(((4-(((4'-chloro-[1,1'-biphenyl]-3-yl)methyl)amino)butyl)thio)methyl)tetrahydrofuran-3,4-diol

参考文献

1. Szewczyk MM, et al. Nat Commun. 2020 May 14;11(1):2396.

SGC8158 (SGC-8158, SGC 8158)

生物&药学活性

物理化学性质&存储条件

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SGC8158 (SGC-8158, SGC 8158)

生物&药学活性

物理化学性质&存储条件

参考文献

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