SGC707 | PRMT3 inhibitor | Probechem Biochemicals

首页-小分子抑制剂&激动剂-Epigenetics-Histone Methyltransferase (HMTase)-SGC707

Chemical Structure : SGC707

CAS No.: 1687736-54-4

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SGC707 (SGC-707)

货号: PC-45680Not For Human Use, Lab Use Only.

SGC707 (SGC 707) is a potent, selective and cell-active allosteric inhibitor of PRMT3 (IC50=31 nM, Kd=53 nM).

规格	价格	库存
10 mg	￥880	In stock
25 mg	￥1380	In stock
50 mg	￥2180	In stock
100 mg		Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SGC707 (SGC 707) is a potent, selective and cell-active allosteric inhibitor of PRMT3 (IC50=31 nM, Kd=53 nM).
SGC707 shows outstanding selectivity against 31 other methyltransferases and more than 250 non-epigenetic targets.
SGC707 is active in cells, also bioavailable and suitable for animal studies.

物理化学性质&存储条件

分子量	298.3397
分子式	C16H18N4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Urea, N-6-isoquinolinyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]-

参考文献

1. Kaniskan HU, et al. Angew Chem Int Ed Engl. 2015 Apr 20;54(17):5166-70.

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SGC707 (SGC-707)

生物&药学活性

物理化学性质&存储条件

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SGC707 (SGC-707)

生物&药学活性

物理化学性质&存储条件

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