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SF235

Chemical Structure : SF235

CAS No.: 2010156-60-0

SF235 (SF 235)

货号: PC-49186Not For Human Use, Lab Use Only.

SF235 is a small-molecule inhibitor of macrophage infectivity potentiator (Mip) protein with IC50 and Ki 0.42 and 0.29 uM against B. pseudomallei Mip (BpMip) peptidyl-prolyl cis/trans isomerase (PPIase) activity, reduce B. pseudomallei virulence in vitro.

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25 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

SF235 is a small-molecule inhibitor of macrophage infectivity potentiator (Mip) protein with IC50 and Ki 0.42 and 0.29 uM against B. pseudomallei Mip (BpMip) peptidyl-prolyl cis/trans isomerase (PPIase) activity, reduce B. pseudomallei virulence in vitro.

物理化学性质&存储条件

分子量 431.507
分子式 C21H25N3O5S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(nicotinamido)ethyl (S)-1-(benzylsulfonyl)piperidine-2-carboxylate

参考文献

1. Jua Iwasaki, et al. J Antimicrob Chemother. 2022 May 29;77(6):1625-1634.

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