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首页-小分子抑制剂&激动剂-JAK/STAT Signaling-STAT-SF-1-088
SF-1-088

Chemical Structure : SF-1-088

CAS No.: 1241832-83-6

SF-1-088

货号: PC-20630Not For Human Use, Lab Use Only.

SF-1-088 is a small molecule STAT5-SH2 domain inhibitor with Ki of 8.3 uM (Stat5b), shows no affinity for Stat1 and Stat3 (Ki>25 uM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

SF-1-088 is a small molecule STAT5-SH2 domain inhibitor with Ki of 8.3 uM (Stat5b), shows no affinity for Stat1 and Stat3 (Ki>25 uM).

物理化学性质&存储条件

分子量 554.61
分子式 C28H30N2O8S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

O=C(O)C1=CC=C(N(CC2=CC=CC=C2)C(CN(C(OC(C)(C)C)=O)S(=O)(C3=CC=C(C)C=C3)=O)=O)C=C1O

参考文献

1. Brent D G Page, et al. J Med Chem. 2012 Feb 9;55(3):1047-55.

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