SF-1-066

Chemical Structure : SF-1-066

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货号: PC-20629Not For Human Use, Lab Use Only.

SF-1-066 is an orally bioavailable inhibitor of STAT3 with IC50 of 35 uM for inhibition of STAT3 DNA binding activity in vitro, binds to the STAT3 SH2 domain and inhibits STAT3 dimerization.

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1 g		Get quote

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生物&药学活性

SF-1-066 is an orally bioavailable inhibitor of STAT3 with IC50 of 35 uM for inhibition of STAT3 DNA binding activity in vitro, binds to the STAT3 SH2 domain and inhibits STAT3 dimerization.

物理化学性质&存储条件

分子量	550.67
分子式	C30H34N2O6S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(N-(4-cyclohexylbenzyl)-2-((N,4-dimethylphenyl)sulfonamido)acetamido)-2-hydroxybenzoic acid

参考文献

1. Page B. D.,et al. Bioorg. Med. Chem. Lett. 21, 5605–5609

2. Diana Resetca, et al. J Biol Chem. 2014 Nov 21;289(47):32538-47.

SF-1-066

生物&药学活性

物理化学性质&存储条件

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SF-1-066

生物&药学活性

物理化学性质&存储条件

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