SCF-I2 |CAS:99827-46-0 Probechem Biochemicals

Chemical Structure : SCF-I2

CAS No.: 99827-46-0

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SCF-I2 (SCF I2)

货号: PC-61192Not For Human Use, Lab Use Only.

SCF-I2 is an allosteric, sepecific inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase with IC50 of 6.2 uM in FP assays.

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10 mg	￥2880	In stock
25 mg	￥4780	In stock
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生物&药学活性

SCF-I2 is an allosteric, sepecific inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase with IC50 of 6.2 uM in FP assays.
SCF-I2 does not affect the activity of the closely related E3 enzyme SCFMet30.
SCF-I2 inhibits binding and/or ubiquitination of both full length Sic1 and Far1 with IC50 of 60 uM.

物理化学性质&存储条件

分子量	342.35
分子式	22H14O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(2-carboxynaphth-1yl)-2-naphthoic acid

参考文献

1. Orlicky S, et al. Nat Biotechnol. 2010 Jul;28(7):733-7.

SCF-I2 (SCF I2)

生物&药学活性

物理化学性质&存储条件

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SCF-I2 (SCF I2)

生物&药学活性

物理化学性质&存储条件

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