欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Androgen Receptor (AR)-SC912
SC912

Chemical Structure : SC912

CAS No.:

加入收藏

SC912 (SC-912)

货号: PC-22067Not For Human Use, Lab Use Only.

SC912 is a small molecule inhibitor of androgen receptor AR-V7, binds to full-length AR as well as AR-V7 through AR N-terminal domain (AR-NTD), disruptes AR-V7 transcriptional activity, impairs AR-V7 nuclear localization and DNA binding.

规格 价格 库存 数量
25 mg Get quote
50 mg Get quote
100 mg Get quote
250 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

SC912 is a small molecule inhibitor of androgen receptor AR-V7, binds to full-length AR as well as AR-V7 through AR N-terminal domain (AR-NTD), disruptes AR-V7 transcriptional activity, impairs AR-V7 nuclear localization and DNA binding.
SC912 suppresses proliferation, induces cell-cycle arrest, and apoptosis in AR-V7 positive CRPC cells.
SC912 attenuates tumor growth and antagonized intratumoral AR signaling in AR-V7 expressing CRPC xenografts.

物理化学性质&存储条件

分子量 493.27
分子式 C22H13Cl2F3N4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3,5-dichloro-N-(2-(3-(3-cyanophenyl)ureido)-5-(trifluoromethyl)phenyl)benzamide

参考文献

1. Qianhui Yi, et al. Oncogene. 2024 Mar 26. doi: 10.1038/s41388-024-02944-2.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: