SC-66 |CAS:871361-88-5 Probechem Biochemicals

Chemical Structure : SC-66

CAS No.: 871361-88-5

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SC-66 (SC66;SC 66)

货号: PC-45738Not For Human Use, Lab Use Only.

SC66 is an allosteric Akt inhibitor, exhibits a dual inhibitory activity that directly interferes with the PH domain binding to PIP3 and facilitates Akt ubiquitination.

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10 mg	￥780	In stock
25 mg	￥1180	In stock
50 mg	￥1880	In stock
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生物&药学活性

SC66 is an allosteric Akt inhibitor, exhibits a dual inhibitory activity that directly interferes with the PH domain binding to PIP3 and facilitates Akt ubiquitination.
SC66 has anticancer activity mouse xenograft tumor model.

物理化学性质&存储条件

分子量	276.3324
分子式	C18H16N2O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 34 mg/mL
Chemical Name/SMILES	Cyclohexanone, 2,6-bis(4-pyridinylmethylene)-, (2E,6E)-

参考文献

1. Jo H, et al. Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6486-91.

2. Cusimano A, et al. Oncotarget. 2015 Jan 30;6(3):1707-22.

SC-66 (SC66;SC 66)

生物&药学活性

物理化学性质&存储条件

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SC-66 (SC66;SC 66)

生物&药学活性

物理化学性质&存储条件

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