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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Protein Phosphatase/PTP-SBI-2130
SBI-2130

Chemical Structure : SBI-2130

CAS No.: 2929401-67-0

SBI-2130 (SBI 2130, SBI2130)

货号: PC-38183Not For Human Use, Lab Use Only.

SBI-2130 (SBI 2130) is a novel furanylbenzamide molecule inhibitor of both WT and oncogenic SHP2 with IC50 of 0.22/5.0 uM for Wt SHP2/SHP2-E76K.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    SBI-2130 (SBI 2130) is a novel furanylbenzamide molecule inhibitor of both WT and oncogenic SHP2 with IC50 of 0.22/5.0 uM for Wt SHP2/SHP2-E76K.

    物理化学性质&存储条件

    分子量 454.5
    分子式 C26H18N2O4S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (Z)-N-(4-aminophenyl)-2-hydroxy-5-(5-((3-oxobenzo[b]thiophen-2(3H)-ylidene)methyl)furan-2-yl)benzamide

    参考文献

    1. Raveendra-Panickar D, et al. J Biol Chem. 2022 Jan;298(1):101477.

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