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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-FABP-SBFI-1143
SBFI-1143

Chemical Structure : SBFI-1143

CAS No.:

SBFI-1143

货号: PC-26227Not For Human Use, Lab Use Only.

SBFI-1143 is a specific small molecule fatty acid binding protein 5 (FABP5) inhibitor with Ki of 0.65 uM, with limited activity against FABP3/FABP7.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

SBFI-1143 is a specific small molecule fatty acid binding protein 5 (FABP5) inhibitor with Ki of 0.65 uM, with limited activity against FABP3/FABP7.

物理化学性质&存储条件

分子量 628.68
分子式 C39H32O8
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(1S,2S,3S,4S)-3-(((4-(benzo[d][1,3]dioxol-5-yl)-[1,1'-biphenyl]-2-yl)oxy)carbonyl)-2,4-bis(2-methoxyphenyl)cyclobutane-1-carboxylic acid

参考文献

1. Shubhra Rajput, et al. Cancers (Basel). 2025 Nov 21;17(23):3723.

2. Yan S, et al. Eur J Med Chem. 2018;154:233–252.

3. Hehe Wang, et al. Bioorg Med Chem. 2025 May 1:122:118136.

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