SBFI-103

Chemical Structure : SBFI-103

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货号: PC-26226Not For Human Use, Lab Use Only.

SBFI-103 is a specific small molecule fatty acid binding protein 5 (FABP5) inhibitor with Ki of 1.72 uM, with limited activity against FABP3/FABP7.

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250 mg		Get quote

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生物&药学活性

SBFI-103 is a specific small molecule fatty acid binding protein 5 (FABP5) inhibitor with Ki of 1.72 uM, with limited activity against FABP3/FABP7.
SBFI-103 produced dose-dependent cytotoxicity in each cell-line tested: PC3 cells with IC50 values of 11.4 and 6.3 μM, respectively.
SBFI-103 (20 mg/kg, daily) inhibits subcutaneous tumor growth.

物理化学性质&存储条件

分子量	534.61
分子式	C34H30O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(1S,2S,3S,4S)-3-(((9H-fluoren-9-yl)methoxy)carbonyl)-2,4-bis(2-methoxyphenyl)cyclobutane-1-carboxylic acid

参考文献

1. Carbonetti G, et al. Prostate. 2020 Jan;80(1):88-98.

2. Yan S, et al. Eur J Med Chem. 2018;154:233–252.

SBFI-103

生物&药学活性

物理化学性质&存储条件

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SBFI-103

生物&药学活性

物理化学性质&存储条件

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