SB33-0223 | TRIM21 inhibitor | Probechem Biochemicals

Chemical Structure : SB33-0223

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SB33-0223 (SB 33-0223)

货号: PC-27969Not For Human Use, Lab Use Only.

SB33-0223 is a small molecule inhibitor of E3 ubiquitin ligase TRIM21, targets the C-terminal PRYSPRY domain of the TRIM21 protein, inhibits TRIM21-mediated ubiquitination of INTS3 by weakening the TRIM21-INTS3 interaction, attenuates cisplatin-induced DNA damage.

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SB33-0223 is a small molecule inhibitor of E3 ubiquitin ligase TRIM21, targets the C-terminal PRYSPRY domain of the TRIM21 protein, inhibits TRIM21-mediated ubiquitination of INTS3 by weakening the TRIM21-INTS3 interaction, attenuates cisplatin-induced DNA damage.

物理化学性质&存储条件

分子量	362.44
分子式	C20H22N6O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzamide, N-[(3R,4S)-4-(3-methyl-1H-1,2,4-triazol-5-yl)-1-(3-pyridinylmethyl)-3-pyrrolidinyl]-, rel-

参考文献

1. Xinyi Dong, et al. Apoptosis. 2026 Aug 31;31(9):216.

SB33-0223 (SB 33-0223)

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物理化学性质&存储条件

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SB33-0223 (SB 33-0223)

生物&药学活性

物理化学性质&存储条件

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