SB 203580 hydrochloride |CAS:869185-85-3 Probechem Biochemicals

Chemical Structure : SB 203580 hydrochloride

CAS No.: 869185-85-3

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SB 203580 hydrochloride (RWJ 64809 hydrochloride;SB203580 hydrochloride;SB-203580 hydrochloride)

货号: PC-42492Not For Human Use, Lab Use Only.

A specific p38 MAPK inhibitor with IC50 of 0.6 uM.

规格	价格	库存
50 mg	￥640	In stock
100 mg	￥960	In stock
200 mg	￥1680	In stock

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生物&药学活性

A specific p38 MAPK inhibitor with IC50 of 0.6 uM; shows selectivity over JNK, p42 MAPK, p90 S6K, p70 S6K, PKA, etc.; suppresses the activation of MAPKAP kinase-2 and prevents the phosphorylation of HSP27 in response to interleukin-1, cellular stresses and bacterial endotoxin in vivo.

物理化学性质&存储条件

分子量	413.8956
分子式	C21H17ClFN3OS
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	H2O: 8.43 mg/mL
Chemical Name/SMILES	Pyridine, 4-[4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl]-, hydrochloride (1:1)

参考文献

1. Cuenda A, et al. FEBS Lett. 1995 May 8;364(2):229-33.

2. Lali FV, et al. J Biol Chem. 2000 Mar 10;275(10):7395-402.

3. Badger AM, et al. J Pharmacol Exp Ther. 1996 Dec;279(3):1453-61.

SB 203580 hydrochloride (RWJ 64809 hydrochloride;SB203580 hydrochloride;SB-203580 hydrochloride)

生物&药学活性

物理化学性质&存储条件

参考文献

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SB 203580 hydrochloride (RWJ 64809 hydrochloride;SB203580 hydrochloride;SB-203580 hydrochloride)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

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