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首页-小分子抑制剂&激动剂-GPCR-5-HT Receptor-SB200646
SB200646

Chemical Structure : SB200646

CAS No.:

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SB200646 (SB-200646A, SB-200646 hydrochloride)

货号: PC-27114Not For Human Use, Lab Use Only.

SB200646 (SB-200646A) is a potent, selective and orally active 5-HT2B/2C receptor antagonist with pKi values of 7.5, 6.9 and 5.2 for 5-HT2B, 5-HT2C and 5-HT2A, respectively, shows electrophysiological and anxiolytic properties.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SB200646 (SB-200646A) is a potent, selective and orally active 5-HT2B/2C receptor antagonist with pKi values of 7.5, 6.9 and 5.2 for 5-HT2B, 5-HT2C and 5-HT2A, respectively, shows electrophysiological and anxiolytic properties.

物理化学性质&存储条件

分子量 302.76
分子式 C15H15ClN4O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(1-Methyl-1H-indol-5-yl)-3-(pyridin-3-yl)urea hydrochloride

参考文献

1. Kennett GA, et al. Br J Pharmacol. 1994 Mar;111(3):797-802.

2. Jackson HC, et al. Br J Pharmacol. 1997 Aug;121(8):1613-8.

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