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首页-小分子抑制剂&激动剂-JAK/STAT Signaling-JAK-SB1578
SB1578

Chemical Structure : SB1578

CAS No.: 937273-04-6

SB1578

货号: PC-22994Not For Human Use, Lab Use Only.

SB1578 is a potent, selective JAK2/FLT3 inhibitor with IC50 of 46/60 nM respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

SB1578 is a potent, selective JAK2/FLT3 inhibitor with IC50 of 46/60 nM respectively.

物理化学性质&存储条件

分子量 462.55
分子式 C26H30N4O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-44-(2-(pyrrolidin-1-yl)ethoxy)-6,11-dioxa-3-aza-2(4,2)-pyrimidina-1(2,5)-furana-4(1,3)-benzenacyclododecaphan-8-ene

参考文献

1. Anthony D William, et al. J Med Chem. 2012 Mar 22;55(6):2623-40.

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