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SB1301

Chemical Structure : SB1301

CAS No.: 2024548-03-4

SB1301 (SB 1301, LIN28-Let-7 inhibitor)

货号: PC-62859Not For Human Use, Lab Use Only.

SB1301 (LIN28-Let-7 inhibitor) is a small-molecule inhibitor disrupting the protein-RNA interaction of LIN28 and Let-7 with FRET IC50 of 4 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SB1301 (LIN28-Let-7 inhibitor) is a small-molecule inhibitor disrupting the protein-RNA interaction of LIN28 and Let-7 with FRET IC50 of 4 uM.
SB1301 (LIN28-Let-7 inhibitor) enhances the production of let-7 miRNAs in Lin28-expressing cancer cells and reduces the level of let-7 target oncogene products.

物理化学性质&存储条件

分子量 583.601
分子式 C31H29N5O7
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(7-(4-((benzyloxy)carbonyl)piperazin-1-yl)-4,4-dimethyl-8-nitrochromeno[4,3-c]pyrazol-1(4H)-yl)benzoic acid

参考文献

1. Lim D, et al. J. Am. Chem. Soc., 2016, 138 (41), pp 13630–13638

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