Chemical Structure : SB1301
CAS No.: 2024548-03-4
货号: PC-62859Not For Human Use, Lab Use Only.
SB1301 (LIN28-Let-7 inhibitor) is a small-molecule inhibitor disrupting the protein-RNA interaction of LIN28 and Let-7 with FRET IC50 of 4 uM.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥2280 | In stock | |
10 mg | ¥3580 | In stock | |
25 mg | ¥5580 | In stock | |
50 mg | Get quote | ||
100 mg | Get quote |
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SB1301 (LIN28-Let-7 inhibitor) is a small-molecule inhibitor disrupting the protein-RNA interaction of LIN28 and Let-7 with FRET IC50 of 4 uM.
SB1301 (LIN28-Let-7 inhibitor) enhances the production of let-7 miRNAs in Lin28-expressing cancer cells and reduces the level of let-7 target oncogene products.
分子量 | 583.601 | |
分子式 | C31H29N5O7 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
4-(7-(4-((benzyloxy)carbonyl)piperazin-1-yl)-4,4-dimethyl-8-nitrochromeno[4,3-c]pyrazol-1(4H)-yl)benzoic acid |
1. Lim D, et al. J. Am. Chem. Soc., 2016, 138 (41), pp 13630–13638
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