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首页-小分子抑制剂&激动剂-Apoptosis-TNF Receptor-SB-U015
SB-U015

Chemical Structure : SB-U015

CAS No.:

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SB-U015 (SB-U 015)

货号: PC-21382Not For Human Use, Lab Use Only.

SB-U015 is a MitoQ derivative and tumor necrosis factor receptor-associated protein 1 (TRAP1) inhibitor.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    SB-U015 is a MitoQ derivative and tumor necrosis factor receptor-associated protein 1 (TRAP1) inhibitor.
    SB-U015 exhibits about 2-fold higher cancer cell-specific cytotoxicity than MitoQ.
    SB-U015 alleviates retinal pathologies via proteolytic HIF1α degradation, which is mediated by opening of the mitochondrial permeability transition pore and activation of calcium-dependent protease calpain-1.

    物理化学性质&存储条件

    分子量 648.84
    分子式 C38H49O5PS
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (10-(4,5-dimethoxy-2-methylphenyl)decyl)triphenylphosphonium methanesulfonate

    参考文献

    1. So-Yeon Kim, et al. Adv Sci (Weinh). 2023 Nov 20:e2302776.

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