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首页-小分子抑制剂&激动剂-Others-Other Targets-SB-583831
SB-583831

Chemical Structure : SB-583831

CAS No.:

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SB-583831 (SB583831)

货号: PC-27048Not For Human Use, Lab Use Only.

SB-583831 is a potent, selective agonist of G‐protein‐coupled receptor GPR132 (G2A) with pEC50 of 7.7 and 7.3 in yeast and β‐arrestin assays (human GPR132a).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

SB-583831 is a potent, selective agonist of G‐protein‐coupled receptor GPR132 (G2A) with pEC50 of 7.7 and 7.3 in yeast and β‐arrestin assays (human GPR132a).
SB-583831 does not activates GPR68 or CB2 in yeast expressing either GPR68 or CB2 up to 100 uM.

物理化学性质&存储条件

分子量 512.21
分子式 C23H18Cl4N2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3',4'-dichloro-N-(2-((3,4-dichlorophenethyl)amino)-2-oxoethyl)-6-hydroxy-[1,1'-biphenyl]-3-carboxamide

参考文献

1. James R Foster, et al. Pharmacol Res Perspect. 2019 Nov 21;7(6):e00542.

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