SB-334867 free base |CAS:792173-99-0 Probechem Biochemicals

Chemical Structure : SB-334867 free base

CAS No.: 792173-99-0

加入收藏

SB-334867 free base (SB334867A free base;SB334867 free base;SB 334867 free base)

货号: PC-42731Not For Human Use, Lab Use Only.

SB-334867 is the first selective Orexin-1 receptor (OX1R) antagonist with pKb of 7.4, displays 50-fold selectivity over OX2R (pKb 5.7).

规格	价格	库存
10 mg	￥880	In stock
25 mg	￥1480	In stock
50 mg	￥2480	In stock
100 mg		Get quote
200 mg		Get quote
1 g		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

SB-334867 is the first selective Orexin-1 receptor (OX1R) antagonist with pKb of 7.4, displays 50-fold selectivity over OX2R (pKb 5.7).
SB-334867 also displays >100-fold or selectivity over 5-HT2B, 5-HT2C and approximately 50 other molecular targets, in particular GPCRs and ion channels.
SB-334867 possesses CNS penetration, in vivo activity following ip dosing.

物理化学性质&存储条件

分子量	319.3174
分子式	C17H13N5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 49 mg/mL
Chemical Name/SMILES	Urea, N-(2-methyl-6-benzoxazolyl)-N'-1,5-naphthyridin-4-yl-

参考文献

1. Smart D, et al. Br J Pharmacol. 2001 Mar;132(6):1179-82.

2. Porter RA, et al. Bioorg Med Chem Lett. 2001 Jul 23;11(14):1907-10.

3. Rodgers RJ, et al. Eur J Neurosci. 2001 Apr;13(7):1444-52.

SB-334867 free base (SB334867A free base;SB334867 free base;SB 334867 free base)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

SB-334867 free base (SB334867A free base;SB334867 free base;SB 334867 free base)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.