SB-277011 hydrochloride (SB277011A)

Chemical Structure : SB-277011 hydrochloride

CAS No.: 215804-67-4

加入收藏

货号: PC-23120Not For Human Use, Lab Use Only.

SB-277011 hydrochloride (SB277011A) is a potent and selective dopamine D3 receptor antagonist with pKi of 8.0.

规格	价格	库存
5 mg	￥880	In stock
10 mg	￥1280	In stock
25 mg	￥2180	In stock
50 mg	￥3580	In stock
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

SB-277011 hydrochloride (SB277011A) is a potent and selective dopamine D3 receptor antagonist with pKi of 8.0.
SB-277011 displays >100-fold selectivity against the D2, 5-HT1B, and 5-HT1D receptors.
SB-277011 exhibits high oral bioavailability and brain penetration in rats.

物理化学性质&存储条件

分子量	475.03
分子式	C28H31ClN4O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((1r,4r)-4-(2-(6-cyano-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)cyclohexyl)quinoline-4-carboxamide hydrochloride

参考文献

1. Stemp G, et al. J Med Chem. 2000 May 4;43(9):1878-85.

2. Reavill C, et al. J Pharmacol Exp Ther. 2000 Sep;294(3):1154-65.

3. Ashby CR Jr, et al. J Pharmacol Exp Ther. 2000 Sep;294(3):1166-74.