SB-0107 (Trapidil, AR-12008)

Chemical Structure : SB-0107

CAS No.: 15421-84-8

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货号: PC-27342Not For Human Use, Lab Use Only.

SB-0107 (Trapidil, AR-12008) is a positive allosteric modulator of a positive allosteric modulator of protein kinase A type II (PKA-II), is also a vasodilator and antiplatelet agent that antagonizes platelet-derived growth factor (PDGF), inhibits phosphodiesterase, thromboxane A2 synthesis and pro-inflammatory cytokine production.

规格	价格	库存
10 mg	￥880	In stock
25 mg	￥1280	In stock
50 mg	￥1980	In stock
100 mg		Get quote

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生物&药学活性

SB-0107 (Trapidil, AR-12008) is a positive allosteric modulator of a positive allosteric modulator of protein kinase A type II (PKA-II), is also a vasodilator and antiplatelet agent that antagonizes platelet-derived growth factor (PDGF), inhibits phosphodiesterase, thromboxane A2 synthesis and pro-inflammatory cytokine production.

物理化学性质&存储条件

分子量	205.27
分子式	C10H15N5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N,N-Diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

参考文献

1. Bordbar A, et al. Sci Transl Med. 2026 Jul 15;18(858):eaec7409.