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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-DNA Repair Protein -SAR-24
SAR-24

Chemical Structure : SAR-24

CAS No.: 1321755-68-3

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SAR-24 (SAR24)

货号: PC-24067Not For Human Use, Lab Use Only.

SAR-24 is a small molecule inhibitor of proliferating cell nuclear antigen (PCNA), significantly affects chromatin-associated PCNA in tumor cells, effectively decreasing its levels and thereby inhibiting cancer cell proliferation.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

SAR-24 is a small molecule inhibitor of proliferating cell nuclear antigen (PCNA), significantly affects chromatin-associated PCNA in tumor cells, effectively decreasing its levels and thereby inhibiting cancer cell proliferation.

物理化学性质&存储条件

分子量 306.32
分子式 C18H14N2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(Z)-2-hydroxy-N'-((2-hydroxynaphthalen-1-yl)methylene)benzohydrazide

参考文献

1. Dillehay KL, et al. Pharmacol Res Perspect. 2015 Mar;3(2):e00115.

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