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首页-小分子抑制剂&激动剂-Wnt/Notch/Hedgehog-Smoothened (Smo)-SANT-2
SANT-2

Chemical Structure : SANT-2

CAS No.: 329196-48-7

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SANT-2 (SANT2)

货号: PC-25923Not For Human Use, Lab Use Only.

SANT-2 is a potent Hh-signaling pathway antagonist and Smoothened receptor antagonist, inhibits Shh-dependent translocation of Smo, interferes with the expression of Gli1.

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10 mg ￥780 In stock
25 mg ￥1280 In stock
50 mg ￥1980 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SANT-2 is a potent Hh-signaling pathway antagonist and Smoothened receptor antagonist, inhibits Shh-dependent translocation of Smo, interferes with the expression of Gli1.

物理化学性质&存储条件

分子量 479.96
分子式 C26H26ClN3O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(3-(1H-Benzo[d]imidazol-2-yl)-4-chlorophenyl)-3,4,5-triethoxybenzamide

参考文献

1. Büttner A, et al. Bioorg Med Chem. 2009 Jul 15;17(14):4943-54.

2. Rominger CM, et al. J Pharmacol Exp Ther. 2009 Jun;329(3):995-1005.

3. Chen JK, et al. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14071-6.

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