SANA

Chemical Structure : SANA

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货号: PC-24788Not For Human Use, Lab Use Only.

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生物&药学活性

SANA is a nitroalkene derivative of salicylate, and a first-in-class activator of creatine-dependent energy expenditure and thermogenesis, induces creatine-dependent thermogenesis and promotes weight loss.
SANA stimulates mitochondrial respiration, a gene expression signature of creatine-dependent thermogenesis and a UCP1-independent loss of weight.
SANA stimulates energy expenditure and protects against obesity under thermoneutral conditions.
SANA stimulates thermogenesis independently of UCP1 expression or activation and does not directly uncouple mitochondria.
SANA is effective for weight loss and weight gain prevention during DIO, but not under normal diet.

物理化学性质&存储条件

分子量	209.16
分子式	C9H7NO5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(2-nitroethenyl)salicylic acid

参考文献

1. Cal K, et al. Nat Metab. 2025 Jun 17. doi: 10.1038/s42255-025-01311-z.

SANA

生物&药学活性

物理化学性质&存储条件

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SANA

生物&药学活性

物理化学性质&存储条件

参考文献

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