SAK3 |CAS:1256269-87-0 Probechem Biochemicals

Chemical Structure : SAK3

加入收藏

SAK3 (T-VGCC enhancer SAK3)

货号: PC-36028Not For Human Use, Lab Use Only.

规格	价格	库存	数量
100 mg		Get quote
250 mg		Get quote
500 mg		Get quote
1 g		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

SAK3 (T-VGCC enhancer SAK3) is a potent, orally acitve enhancer of T-type voltage-gated Ca2+ channel (T-VGCC), enhances CaV3.1 and CaV3.3, but not CaV3.2 activity at concentrations of 0.01-10 nM in neuro2A cells in vitro; significantly enhanced acetylcholine (ACh) release in the hippocampal CA1 region of naïve mice (0.5 mg/kg, p.o.); significantly enhanced hippocampal ACh levels in olfactory-bulbectomized (OBX) mice, rescuing impaired memory-related behaviors.

物理化学性质&存储条件

分子量	369.421
分子式	C20H23N3O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Ethyl 8'-methyl-2',4-dioxo-2-(piperidin-1-yl)-2'H-spiro[cyclopent[2]ene-1,3'-imidazo[1,2-a]pyridine]-3-carboxylate

参考文献

1. Yabuki Y, et al. Neuropharmacology. 2017 May 1;117:1-13.

2. Izumi H, et al. Neuroscience. 2018 May 1;377:87-97.

3. Husain N, et al. Pharmacology. 2018;101(5-6):309-321.

4. Wang S, et al. PLoS One. 2018 Dec 20;13(12):e0206986.

SAK3 (T-VGCC enhancer SAK3)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

SAK3 (T-VGCC enhancer SAK3)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.