SA57 | FAAH/MAGL inhibitor Probechem Biochemicals

Chemical Structure : SA57

加入收藏

SA57 (SA-57, dual FAAH/MAGL inhibitor)

货号: PC-60706Not For Human Use, Lab Use Only.

SA57a is a highly potent and selective dual FAAH/MAGL inhibitor with IC50 of 1-3 nM against FAAH, inhibits mouse (IC50=410 nM) and human (IC50=1.4 uM) MAGL.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

SA57a is a highly potent and selective dual FAAH/MAGL inhibitor with IC50 of 1-3 nM against FAAH, inhibits mouse (IC50=410 nM) and human (IC50=1.4 uM) MAGL.
SA57 also inhibits the 2-AG hydrolases MAGL and ABHD6, but not other brain serine hydrolases.
SA57 produces antiwithdrawal effects in morphine-dependent mice, and does not elicit any cannabimimetic side effects.

物理化学性质&存储条件

分子量	338.832
分子式	C17H23ClN2O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-[2-(4-chlorophenyl)ethyl]-1-piperidinecarboxylic acid 2-(methylamino)-2-oxoethyl ester

参考文献

1. Niphakis MJ, et al. ACS Chem Neurosci. 2012 May 16;3(5):418-26.

2. Ramesh D, et al. Neuropsychopharmacology. 2013 May;38(6):1039-49.

3. Wiebelhaus JM, et al. J Pharmacol Exp Ther. 2015 Feb;352(2):195-207.

4. Wilkerson JL, et al. Neuropharmacology. 2017 Mar 1;114:156-167.

SA57 (SA-57, dual FAAH/MAGL inhibitor)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

SA57 (SA-57, dual FAAH/MAGL inhibitor)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.